Nintendo recently released Super Mario Run for iOS devices (with it coming to Android devices this year) to great success, but Mario in his iOS adventure offers some features/elements not seen in his other 2D ventures. GameXplain noticed this and posted the above video on their YouTube channel.
They offer five key points which include Mario having higher agility so he can vault over objects/enemies, use coins to expand levels & locations, and retooling the life system to replace it with bubbles. These are changes I think will help make 2D Mario even more accessible for gamers.